Guido Werner Alves
Professor
Contact
Email: guido.alves@uis.no
Department
Faculty of Science and Technology
Department of Chemistry, Bioscience and Environmental Engineering
Publications
Vitenskapelige publikasjoner
Eidem, Live Egeland; Birkeland, Even; Austdal, Marie; Bårdsen, Kjetil; Lange, Johannes; Alves, Guido Werner; Berven, Frode Steingrimsen; Nilsen, Mari Mæland; Herlofson, Karen; Tysnes, Ole-Bjørn; Omdal, Roald
(2024)
Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid.Movement Disorders.
ISSN 0885-3185.
Volum 39.
Hefte 4.
DOI: 10.1002/mds.29715
Flønes, Irene; Toker, Lilah; Sandnes, Dagny Ann; Castelli, Martina Galatea; Mostafavi, Sepideh; Lura, Njål; Shadad, Omnia; Fernandez-Vizarra, Erika; Painous, Cèlia; Pérez-Soriano, Alexandra; Compta, Yaroslau; Molina-Porcel, Laura; Alves, Guido Werner; Tysnes, Ole-Bjørn; Dölle, Christian; Sanchez Nido, Gonzalo; Tzoulis, Charalampos
(2024)
Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease.Nature Communications.
ISSN 2041-1723.
Volum 15.
Hefte 1.
Hiorth, Ylva Hivand; Schulz, Jörn; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner
(2024)
Orthostatic Hypotension and Risk of Mild Cognitive Impairment and Dementia in Parkinson's Disease.Movement Disorders Clinical Practice.
ISSN 2330-1619.
DOI: 10.1002/mdc3.14179
Pedersen, Camilla Christina; Ushakova, Anastasia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Blennow, Kaj; Zetterberg, Henrik; Maple-Grødem, Jodi; Lange, Johannes
(2024)
Serum neurofilament light at diagnosis: a prognostic indicator for accelerated disease progression in Parkinson’s Disease.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 10.
Dick, Fiona; Johanson, Gard Aasmund Skulstad; Tysnes, Ole-Bjørn; Alves, Guido Werner; Dölle, Christian; Tzoulis, Charalampos
(2024)
Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy.Molecular Neurobiology.
ISSN 0893-7648.
Dick, Fiona; Tysnes, Ole-Bjørn; Alves, Guido Werner; Sanchez Nido, Gonzalo; Tzoulis, Charalampos
(2023)
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease.iScience.
ISSN 2589-0042.
Volum 26.
Hefte 2.
Erga, Aleksander Hagen; Alves, Guido Werner; Leentjens, Albert F.G.
(2023)
The ePark study protocol: A decentralized trial of individual video-assisted cognitive behavioural therapy for depressive disorder in Parkinson's disease.Contemporary Clinical Trials Communications.
ISSN 2451-8654.
Volum 32.
Gonzalez Velez, Maria Camila; Tovar-Rios, Diego Alejandro; Alves, Guido Werner; Dalen, Ingvild; Williams-Gray, Caroline H.; Camacho, Marta; Forsgren, Lars; Bäckström, David; Lawson, Rachael A.; Macleod, Angus D.; Counsell, Carl E.; Paquet, Claire; DeLena, Carlo; D'Antonio, Fabrizia; Pilotto, Andrea; Padovani, Alessandro; Blanc, Frédéric; Falup-Pecurariu, Cristian; Lewis, Simon J.G.; Rejdak, Konrad; Papuc, Ewa; Hort, Jakub; Nedelska, Zuzana; O'Brien, John; Bonanni, Laura; Marquié, Marta; Boada, Mercè; Pytel, Vanesa; Abdelnour, Carla; Alcolea, Daniel; Beyer, Katrin; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi
(2023)
Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia.Movement Disorders Clinical Practice.
ISSN 2330-1619.
Volum 10.
Hefte 6.
s.980-986.
DOI: 10.1002/mdc3.13752
Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes
(2023)
Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson's Disease.Journal of Parkinson's Disease.
ISSN 1877-7171.
Volum 13.
Hefte 5.
s.841-844.
DOI: 10.3233/JPD-230065
Maple-Grødem, Jodi; Ushakova, Anastasia; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes
(2023)
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach.Neurobiology of Disease.
ISSN 0969-9961.
Volum 186.
Pedersen, Camilla Christina; Ushakova, Anastasia; Skogseth, Ragnhild Eide; Alves, Guido Werner; Tysnes, Ole-Bjørn; Aarsland, Dag; Lange, Johannes; Maple-Grødem, Jodi
(2023)
Inflammatory biomarkers in newly diagnosed patients with Parkinson’s disease and related neurodegenerative disorders.Neurology: Neuroimmunology and neuroinflammation.
ISSN 2332-7812.
Volum 10.
Hefte 4.
Tufekcioglu, Zeynep; Lange, Johannes; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner; Emre, Murat
(2023)
Cognitive Profile in Parkinson’s Disease Dementia Patients with Low versus Normal Cerebrospinal Fluid Amyloid Beta.Dementia and Geriatric Cognitive Disorders Extra.
ISSN 1664-5464.
Volum 13.
Hefte 1.
s.39-47.
DOI: 10.1159/000534552
Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Alves, Guido Werner; Bergsland, Niels; Myhr, Kjell-Morten; Zetterberg, Henrik; Zivadinov, Robert; Farbu, Elisabeth
(2023)
Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study.Acta Neurologica Scandinavica.
ISSN 0001-6314.
Volum 2023.
DOI: 10.1155/2023/7136599
Guitton, Romain Guillaume Bernard; Dölle, Christian; Alves, Guido Werner; Tysnes, Ole-Bjørn; Nido, Gonzalo Sanchez; Tzoulis, Charalampos
(2022)
Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA.Epigenetics.
ISSN 1559-2294.
Erga, Aleksander Hagen; Maple-Grødem, Jodi; Alves, Guido Werner
(2022)
Cannabis use in Parkinson’s disease—A nationwide online survey study.Acta Neurologica Scandinavica.
ISSN 0001-6314.
Volum 145.
Hefte 6.
s.692-697.
DOI: 10.1111/ane.13602
Borda, Miguel Germán; Perez-Zepeda, Mario Ulises; Jaramillo-Jiménez, Alberto; Chaudhuri, K. Ray; Tovar-Rios, Diego Alejandro; Wallace, Lindsey; Batzu, Lucia; Rockwood, Kenneth; Tysnes, Ole-Bjørn; Aarsland, Dag; Alves, Guido Werner
(2022)
Frailty in Parkinson's disease and its association with early dementia: A longitudinal study.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 99.
s.51-57.
Flønes, Irene Hana; Nyland, Harald; Sandnes, Dagny Ann; Alves, Guido Werner; Tysnes, Ole-Bjørn; Tzoulis, Charalampos
(2022)
Early Forms of α-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson’s Disease.Biomolecules.
ISSN 2218-273X.
Volum 12.
Hefte 6.
s.1-12.
DOI: 10.3390/biom12060747
Szwedo, Aleksandra Anna; Dalen, Ingvild; Pedersen, Kenn Freddy; Camacho, Marta; Bäckström, David; Forsgren, Lars; Tzoulis, Charalampos; Winder-Rhodes, Sophie; Hudson, Gavin; Liu, Ganqiang; Scherzer, Clemens R.; Lawson, Rachael A.; Yarnall, Alison J.; Williams-Gray, Caroline H.; Macleod, Angus D.; Counsell, Carl E.; Tysnes, Ole-Bjørn; Alves, Guido Werner; Maple-Grødem, Jodi
(2022)
GBA and APOE Impact Cognitive Decline in Parkinson's Disease: A 10-Year Population-Based Study.Movement Disorders.
ISSN 0885-3185.
Volum 37.
Hefte 5.
s.1016-1027.
DOI: 10.1002/mds.28932
Gonzalez Velez, Maria Camila; Dalen, Ingvild; Maple-Grødem, Jodi; Tysnes, Ole-Bjørn; Alves, Guido Werner
(2022)
Parkinson’s disease clinical milestones and mortality.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 8.
Hefte 1.
Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Dalen, Ingvild; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes
(2022)
Association of CSF Glucocerebrosidase Activity with the Risk of Incident Dementia in Patients with Parkinson Disease.Neurology.
ISSN 0028-3878.
Volum 100.
Hefte 4.
s.e388-e395.
Liu, Ganqiang; Ni, Chunming; Zhan, Jiamin; Li, Weimin; Luo, Junfeng; Liao, Zhixiang; Locascio, Joseph J.; Xian, Wenbiao; Chen, Ling; Pei, Zhong; Corvol, Jean-Christophe; Maple-Grødem, Jodi; Campbell, Meghan C.; Elbaz, Alexis; Lesage, Suzanne; Brice, Alexis; Hung, Albert Y.; Schwarzschild, Michael A.; Hayes, Michael T.; Wills, Anne-Marie; Ravina, Bernard; Shoulson, Ira; Taba, Pille; Kõks, Sulev; Beach, Thomas G.; Cormier-Dequaire, Florence; Alves, Guido Werner; Tysnes, Ole-Bjørn; Perlmutter, Joel S.; Heutink, Peter; van Hilten, Jacobus J.; Barker, Roger A.; Williams-Gray, Caroline H.; Scherzer, Clemens R.
(2022)
Mitochondrial haplogroups and cognitive progression in Parkinson’s disease.Brain.
ISSN 0006-8950.
Volum 146.
Hefte 1.
s.42-49.
Pedersen, Camilla Christina; Lange, Johannes; Førland, Marthe Gurine; Macleod, Angus D.; Alves, Guido Werner; Maple-Grødem, Jodi
(2021)
A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 7.
Szwedo, Aleksandra Anna; Pedersen, Camilla Christina; Ushakova, Anastasia; Forsgren, Lars; Tysnes, Ole-Bjørn; Counsell, Carl E.; Alves, Guido Werner; Lange, Johannes; Macleod, Angus D.; Maple-Grødem, Jodi
(2021)
Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients.Frontiers in Neurology.
ISSN 1664-2295.
Volum 11.
s.1-7.
Toker, Lilah; Tran, Gia T.; Sundaresan, Janani; Tysnes, Ole-Bjørn; Alves, Guido; Haugarvoll, Kristoffer; Nido, Gonzalo Sanchez; Dölle, Christian; Tzoulis, Charalampos
(2021)
Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain.Molecular Neurodegeneration.
ISSN 1750-1326.
Volum 16.
Hefte 1.
s.1-20.
Grødem, Jodi Maple; Paul, Kimberly C.; Dalen, Ingvild; Ngo, Kathie J.; Wong, Darice; Macleod, Angus D.; Counsell, Carl E.; Bäckström, David; Forsgren, Lars; Tysnes, Ole-Bjørn; Kusters, Cynthia D.J. ; Fogel, Brent L.; Bronstein, Jeff M.; Ritz, Beate; Alves, Guido Werner
(2021)
Lack of Association between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts.Journal of Parkinson's Disease.
ISSN 1877-7171.
Volum 11.
Hefte 4.
s.1569-1578.
DOI: 10.3233/jpd-212657
Camacho, Marta; Macleod, Angus D.; Grødem, Jodi Maple; Evans, Jonathan R.; Breen, David P.; Cummins, G; Wijeyekoon, Ruwani; Greenland, Julia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Lawson, Rachel A.; Barker, Roger A.; Williams-Gray, Caroline H.
(2021)
Early constipation predicts faster dementia onset in Parkinson's disease.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 7.
s.1-7.
Grødem, Jodi Maple; Dalen, Ingvild; Tysnes, Ole-Bjørn; Macleod, Angus D.; Forsgren, Lars; Counsell, Carl E.; Alves, Guido Werner
(2021)
Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease.Neurology.
ISSN 0028-3878.
Volum 96.
Hefte 7.
s.e1036-e1044.
Liu, Ganqiang; Peng, Jiajie; Liao, Zhixiang; Locascio, Joseph J.; Corvol, Jean-Christophe; Zhu, Frank; Dong, Xianjun; Grødem, Jodi Maple; Campbell, Meghan C; Elbaz, Alexis; Lesage, Suzanne; Brice, Alexis; Mangone, Graziella; Growdon, John H.; Hung, Albert Y; Schwarzschild, Michael A.; Hayes, Michael T; Wills, Anne-Marie; Herrington, Todd M; Ravina, Bernard; Shoulson, Ira; Taba, Pille; Kõks, Sulev; Beach, Thomas G.; Cormier-Dequaire, Florence; Alves, Guido Werner; Tysnes, Ole-Bjørn; Perlmutter, Joel S; Heutink, Peter; Amr, Sami S; Van Hilten, Jacobus; Kasten, Meike; Mollenhauer, Brit; Trenkwalder, Claudia; Klein, Christine; Barker, Roger A.; Williams-Gray, Caroline H.; Marinus, Johan; Scherzer, Clemens R.
(2021)
Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease.Nature Genetics.
ISSN 1061-4036.
Volum 53.
s.787-793.
Chung, Janete; Ushakova, Anastasia; Doitsidou, Maria; Tzoulis, Charalampos; Tysnes, Ole-Bjørn; Dalen, Ingvild; Pedersen, Kenn Freddy; Alves, Guido Werner; Maple-Grødem, Jodi
(2021)
The impact of common genetic variants in cognitive decline in the first seven years of Parkinson's disease: A longitudinal observational study.Neuroscience Letters.
ISSN 0304-3940.
Volum 764.
s.1-7.
Hiorth, Ylva Hivand; Alves, Guido Werner; Nilsson, Maria H.
(2021)
Fysisk aktivitet vid Parkinsons sjukdom. I: Fysisk aktivitet i sjukdomsprevention och sjukdomsbehandling, FYSS 2021..
ISBN 978-91-985098-2-3.
s.423-426.
Lauvsnes, Maria Boge; Zetterberg, Henrik; Blennow, Kaj; Kvaløy, Jan Terje; Tjensvoll, Anne Bolette; Maroni, Stian; Beyer, Mona K.; Greve, Ole Jacob; Kvivik, Ingeborg; Alves, Guido Werner; Gøransson, Lasse Gunnar; Harboe, Erna; Hirohata, Shunsei; Omdal, Roald
(2021)
Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus.Journal of Neurology.
ISSN 0340-5354.
Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Bergsland, Niels; Zivadinov, Robert; Alves, Guido Werner; Myhr, Kjell-Morten; Farbu, Elisabeth
(2021)
CSF neurofilament light chain predicts 10-year clinical and radiologic worsening in multiple sclerosis.Multiple Sclerosis Journal, Experimental, Translational and Clinical.
ISSN 2055-2173.
Volum 7.
Hefte 4.
s.1-10.
Erga, Aleksander Hagen; Alves, Guido Werner; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy
(2020)
Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 78.
s.27-30.
Borda, Miguel Germán; Aarsland, Dag; Tovar-Rios, Diego Alejandro; Melvær, Giil Lasse; Ballard, Clive; Gonzalez Velez, Maria Camila; Brønnick, Kolbjørn Kallesten; Alves, Guido Werner; Oppedal, Ketil; Sønnesyn, Hogne; Vik-Mo, Audun Osland
(2020)
Neuropsychiatric symptoms and functional decline in Alzheimerʼs disease and Lewy body dementia.Journal of The American Geriatrics Society.
ISSN 0002-8614.
Volum 68.
Hefte 10.
s.2257-2263.
DOI: 10.1111/jgs.16709
Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton; Makarious, Mary B.; Kim, Jonggeol J.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Smolensky, Luba; Amondikar, Ninad; Hutten, Samantha J.; Frasier, Mark; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; Van Deerlin, Vivianna M.; Hernandez, Dena G.; Gibbs, Raphael; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Andreassen, Ole Andreas; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B.; Nalls, Mike A.
(2020)
Differences in the presentation and progression of Parkinson's disease by sex.Movement Disorders.
ISSN 0885-3185.
s.1-14.
DOI: 10.1002/mds.28312
Ongre, Solgunn; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner; Herlofson, Karen
(2020)
Progression of fatigue in Parkinson’s disease – a 9-year follow-up.European Journal of Neurology.
ISSN 1351-5101.
Volum 28.
Hefte 1.
s.108-116.
DOI: 10.1111/ene.14520
Gaare, Johannes Jernqvist; Sanchez Nido, Gonzalo; Dölle, Christian; Sztromwasser, Pawel Szymon; Alves, Guido Werner; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Tzoulis, Charalampos
(2020)
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci.PLOS ONE.
ISSN 1932-6203.
Volum 15.
Hefte 10.
s.1-9.
Sanchez Nido, Gonzalo; Dick, Fiona; Toker, Lilah; Petersen, Kjell; Alves, Guido Werner; Tysnes, Ole-Bjørn; Jonassen, Inge; Haugarvoll, Kristoffer; Tzoulis, Charalampos
(2020)
Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition.Acta neuropathologica communications.
ISSN 2051-5960.
Volum 8.
s.1-14.
Tjensvoll, Anne Bolette; Lauvsnes, Maria Boge; Zetterberg, Henrik; Kvaløy, Jan Terje; Kvivik, Ingeborg; Maroni, Stian; Greve, Ole Jacob; Beyer, Mona K.; Hirohata, Shunsei; Putterman, Chaim; Alves, Guido Werner; Harboe, Erna; Blennow, Kaj; Gøransson, Lasse; Omdal, Roald
(2020)
Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren’s syndrome.Journal of Neurology.
ISSN 0340-5354.
Dick, Fiona; Sanchez Nido, Gonzalo; Alves, Guido Werner; Tysnes, Ole-Bjørn; Nilsen, Gry Hilde; Dölle, Christian; Tzoulis, Charalampos
(2020)
Differential transcript usage in the Parkinson’s disease brain.PLoS Genetics.
ISSN 1553-7390.
Volum 16.
Hefte 11.
s.1-24.
Kusters, Cynthia D.J.; Paul, Kimberly C.; Folle, Aline Duarte; Keener, Adrienne M.; Bronstein, Jeff M.; Dobricic, Valerija; Tysnes, Ole-Bjørn; Bertram, Lars; Alves, Guido Werner; Sinsheimer, Janet S.; Lill, Christina M.; Maple-Grødem, Jodi; Ritz, Beate R.
(2020)
Genetic risk scores and hallucinations in patients with Parkinson disease.Neurology: Genetics.
ISSN 2376-7839.
Volum 6.
Hefte 5.
Oftedal, Linn; Maple-Grødem, Jodi; Førland, Marthe Gurine; Alves, Guido Werner; Lange, Johannes
(2020)
Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid.Scientific Reports.
ISSN 2045-2322.
Volum 10.
s.1-8.
Ramsay, Neil; Macleod, Angus D.; Alves, Guido Werner; Camacho, Marta; Forsgren, Lars; Lawson, Rachel A.; Maple-Grødem, Jodi; Tysnes, Ole-Bjørn; Williams-Gray, Caroline H.; Yarnall, Alison J.; Counsell, Carl E.
(2020)
Validation of a UPDRS-/MDS-UPDRS-based definition of functional dependency for Parkinson's disease.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 76.
s.49-53.
Radder, Danique L M; Nonnekes, Jorik; van Nimwegen, Marlies; Eggers, Carsten; Abbruzzese, Giovanni; Alves, Guido Werner; Browner, Nina; Chaudhuri, K Ray; Ebersbach, Georg; Ferreira, Joaquim J.; Fleisher, Jori; Fletcher, Peter; Frazzitta, Giuseppe; Giladi, Nir; Guttman, Mark; Iansek, Robert; Khandhar, Suketu; Klucken, Jochen; Lafontaine, Anne-Louise; Marras, Connie; Nutt, John; Okun, Michael S.; Parashos, Sotirions A.; Munneke, Marten; Bloem, Bastiaan R.
(2020)
Recommendations for the Organization of Multidisciplinary Clinical Care Teams in Parkinson's Disease.Journal of Parkinson's Disease.
ISSN 1877-7171.
Volum 10.
Hefte 3.
s.1087-1098.
DOI: 10.3233/JPD-202078
Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir
(2019)
Combinatory microRNA serum signatures as classifiers of Parkinson's disease.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 64.
s.202-210.
Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes
(2019)
The value of cerebrospinal fluid alpha-synuclein and the tau/alpha-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology.European Journal of Neurology.
ISSN 1351-5101.
Volum 27.
Hefte 1.
s.43-50.
DOI: 10.1111/ene.14032
Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton L.; Kim, Jonggeol J.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Hutten, Samantha J.; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; Van Deerlin, Vivianna M.; Hernandez, Dena G.; Gibbs, J. Raphael; Chitrala, Kumaraswamy Naidu; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Andreassen, Ole Andreas; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B.; Nalls, Mike A.
(2019)
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts.Movement Disorders.
ISSN 0885-3185.
Volum 34.
Hefte 12.
s.1839-1850.
DOI: 10.1002/mds.27845
Erga, Aleksander Hagen; Alves, Guido Werner; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy
(2019)
Evolution of impulsive–compulsive behaviors and cognition in Parkinson’s disease.Journal of Neurology.
ISSN 0340-5354.
Volum 267.
Hefte 1.
s.259-266.
Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton L.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Hutten, Samantha J.; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; van Deerlin, Vivianna M.; Hernandez, Dena G.; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B.; Nalls, Mike A.
(2019)
Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts.Neurology: Genetics.
ISSN 2376-7839.
Volum 5.
Hefte 4.
s.1-14.
Hiorth, Ylva Hivand; Pedersen, Kenn Freddy; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner
(2019)
Orthostatic hypotension in Parkinson disease: A 7-year prospective population-based study.Neurology.
ISSN 0028-3878.
Volum 93.
Hefte 16.
s.e1526-e1534.
Sanchez Nido, Gonzalo; Dölle, Christian; Flønes, Irene Hana; Tuppen, Helen A.; Alves, Guido; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Tzoulis, Charalampos
(2018)
Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease.Neurobiology of Aging.
ISSN 0197-4580.
Volum 63.
s.120-127.
Førland, Marthe Gurine; Öhrfelt, Annika; Dalen, Ingvild; Tysnes, Ole-Bjørn; Blennow, Kaj; Zetterberg, Henrik; Pedersen, Kenn Freddy; Alves, Guido; Lange, Johannes
(2018)
Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease.Parkinsonism & Related Disorders.
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Dopaminergic and opioid pathways associated with impulse control disorders in Parkinson's disease.Frontiers in Neurology.
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Maple-Grødem, Jodi; Chung, Janete; Lunde, Kristin Aaser; Tzoulis, Charalampos; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy; Alves, Guido
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Alzheimer disease associated variants in SORL1 accelerate dementia development in Parkinson disease.Neuroscience Letters.
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Lunde, Kristin Aaser; Chung, Janete; Dalen, Ingvild; Pedersen, Kenn Freddy; Linder, Jan; Domellöf, Magdalena E; Elgh, Eva; Macleod, Angus D.; Tzoulis, Charalampos; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Forsgren, Lars; Counsell, Carl E.; Alves, Guido; Maple-Grødem, Jodi
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Association of glucocerebrosidase polymorphisms and mutations with dementia in incident Parkinson's disease.Alzheimer's & Dementia.
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Rare genetic variation in mitochondrial pathways influences the risk for parkinson's disease.Movement Disorders.
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Herlofson, Karen; Heijnen, Cobi Johanna; Lange, Johannes; Alves, Guido; Tysnes, Ole-Bjørn; Friedman, Joseph Harold; Fagundes, Christopher P.
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Inflammation and fatigue in early, untreated Parkinson's Disease.Acta Neurologica Scandinavica.
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Gjerde, Kristian Varden; Mueller, Bernd; Skeie, Geir Olve; Assmus, Jörg; Alves, Guido; Tysnes, Ole-Bjørn
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Hyposmia in a simple smell test is associated with accelerated cognitive decline in early Parkinson's disease.Acta Neurologica Scandinavica.
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Kurtishi, Alberim; Rosen, Benjamin; Patil, Ketan S.; Alves, Guido Werner; Møller, Simon Geir
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Cellular Proteostasis in Neurodegeneration.Molecular Neurobiology.
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Gjerstad, Michaela D; Alves, Guido Werner; Maple-Grødem, Jodi
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Excessive Daytime Sleepiness and REM Sleep Behavior Disorders in Parkinson's Disease: A Narrative Review on Early Intervention With Implications to Neuroprotection.Frontiers in Neurology.
ISSN 1664-2295.
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Erga, Aleksander Hagen; Gjerstad, Michaela D; Alves, Guido Werner; Pedersen, Kenn Freddy
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Psykologisk behandling av ikke-motoriske symptomer ved parkinsons sykdom.
Tidsskrift for Norsk Psykologforening.
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Kristiansen, Madeleine; Maple-Grødem, Jodi; Alves, Guido Werner; Arepalli, Sampath; Hernandez, Dena G; Iwaki, Hirotaka; Nalls, Mike A; Singleton, Andrew; Tysnes, Ole-Bjørn; Toft, Mathias; Pihlstrøm, Lasse
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A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease.Movement Disorders.
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Erga, Aleksander Hagen; Alves, Guido; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy
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Impulsive and Compulsive Behaviors in Parkinson’s Disease: The Norwegian ParkWest Study.Journal of Parkinson's Disease.
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Flønes, Irene Hana; Fernandez-Vizarra, Erika; Lykouri, Maria; Brakedal, Brage; Skeie, Geir Olve; Miletic, Hrvoje; Lilleng, Peer Kåre; Alves, Guido; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Dölle, Christian; Zeviani, Massimo; Tzoulis, Charalampos
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Prodromal markers in Parkinson's disease: Limitations in longitudinal studies and lessons learned.Frontiers in Aging Neuroscience.
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Loss of independence in early Parkinson disease: A 5-year population-based incident cohort study.Neurology.
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Subcellular Parkinson’s disease-specific alpha-synuclein species show altered behavior in neurodegeneration.Molecular Neurobiology.
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Reliability of three disability scales for detection of independence loss in Parkinson's Disease.Parkinson's Disease.
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Long-term risk of falls in an incident Parkinson's disease cohort: the Norwegian ParkWest study..Journal of Neurology.
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Validation of a new assay for α-synuclein detection in cerebrospinal fluid.Clinical Chemistry and Laboratory Medicine.
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LRRK2 Knockdown in Zebrafish Causes Developmental Defects, Neuronal Loss, and Synuclein Aggregation .Journal of Neuroscience Research.
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A 12-year population-based study of freezing of gait in Parkinson's disease.Parkinsonism & Related Disorders.
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Association of a BACE1 gene polymorphism with Parkinson's disease in a Norwegian population.Parkinson's Disease.
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A Proteomics Approach to Investigate miR- 153-3p and miR-205-5p Targets in Neuroblastoma Cells.PLOS ONE.
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microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases.Cellular and Molecular Life Sciences (CMLS).
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Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease-Report of the JPND Working Group BioLoC-PD.Neuroepidemiology.
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New insight into neurodegeneration: The role of proteomics.Molecular Neurobiology.
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CSF Aβ42 predicts early-onset dementia in Parkinson disease.Neurology.
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New Insight into Neurodegeneration: the Role of Proteomics.Molecular Neurobiology.
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Cerebrospinal fluid A levels correlate with structural brain changes in Parkinson's disease.Movement Disorders.
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Prognosis of Mild Cognitive Impairment in Early Parkinson Disease.JAMA Neurology.
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Psychometric Properties of the Starkstein Apathy Scale in Patients With Early Untreated Parkinson Disease.The American journal of geriatric psychiatry.
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Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment.Neurobiology of Aging.
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CSF amyloid beta 38 as a novel diagnostic marker for dementia with Lewy bodies.Journal of Neurology, Neurosurgery and Psychiatry.
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Verbal memory in drug-naive, newly diagnosed Parkinson's Disease. The retrieval deficit hypothesis revisited.Neuropsychology.
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Ventricular enlargement and mild cognitive impairment in early Parkinson's Disease.Movement Disorders.
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Apathy in drug-naïve patients with incident Parkinson's disease: the Norwegian ParkWest study.Journal of Neurology.
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A 12-Year Population-Based Study of Psychosis in Parkinson Disease.Archives of Neurology.
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Brain Atrophy and White Matter Hyperintensities in Early Parkinson's Disease.Movement Disorders.
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Bøker og kapitler
Bjørnestad, Anders; Alves, Guido
(2017)
Motor and non-motor challenges in early Parkinson’s disease.
Universitetet i Bergen.
ISBN 978-82-308-3895-2.
Formidling
Lauvsnes, Maria Boge; Zetterberg, Henrik; Blennow, Kaj; Kvaløy, Jan Terje; Tjensvoll, Anne Bolette; Maroni, Stian; Beyer, Mona K.; Greve, Ole Jacob; Kvivik, Ingeborg; Alves, Guido Werner; Gøransson, Lasse Gunnar; Harboe, Erna; Hirohata, Shunsei; Omdal, Roald
(2024)
Correction to: Neurofilament light in plasma is a potential biomarker of central nervous system involvement in systemic lupus erythematosus (Journal of Neurology, (2022), 269, 6, (3064-3074), 10.1007/s00415-021-10893-z).Journal of Neurology.
ISSN 0340-5354.
Dietrichs, Espen; Alves, Guido Werner; Benjaminsen, Espen; Johansen, Krisztina Kunszt; Tysnes, Ole-Bjørn
(2023)
Behandling av motoriske symptomer ved Parkinsons sykdom.Tidsskrift for Den norske legeforening.
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Erga, Aleksander Hagen; Alves, Guido Werner; Leentjens, Albert F.G.
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Corrigendum to “The ePark study protocol: A decentralized trial of individual video-assisted cognitive behavioural therapy for depressive disorder in Parkinson's disease” [Contemp. Clinic. Trials Commun. 32 (2023) 101080](S2451865423000261)(10.1016/j.conctc.2023.101080).Contemporary Clinical Trials Communications.
ISSN 2451-8654.
Oftedal, Linn Silje Wathne; Lange, Johannes; Pedersen, Kenn Freddy; Erga, Aleksander Hagen; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner; Maple-Grødem, Jodi
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Early GCase activity is a predictor of long-term cognitive decline in Parkinson’s disease.Translational Neurodegeneration.
ISSN 2096-6466.
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E. Dietrichs og medarbeidere svarer.Tidsskrift for Den norske legeforening.
ISSN 0029-2001.
Volum 143.
Hefte 12.
Ongre, Solgunn; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner; Herlofson, Karen
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Letter to the editor in response to the letter from the EPIPARK Study Group regarding the publication ʻProgression of fatigue in Parkinson's disease - a 9-year follow-upʼ (Eur J Neurol 2021. doi:10.1111/ene.14520).European Journal of Neurology.
ISSN 1351-5101.
Volum 28.
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s.e33-e34.
DOI: 10.1111/ene.14765
Hiorth, Ylva Hivand; Pedersen, Kenn Freddy; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner
(2019)
ORTHOSTATIC HYPOTENSION IN PARKINSON’S DISEASE: A SEVEN-YEAR PROSPECTIVE POPULATION-BASED STUDY .
The 14th International conference on Alzheimer's & Parkinson's Disease;
2019-03-29 - 2019-03-30.
Gaare, Johannes Jernqvist; Sanchez Nido, Gonzalo; Sztromwasser, Pawel Szymon; Knappskog, Per; Dahl, Olav; Lund-Johansen, Morten; Alves, Guido; Tysnes, Ole-Bjørn; Johansson, Stefan; Haugarvoll, Kristoffer; Tzoulis, Charalampos
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No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson's disease.Brain.
ISSN 0006-8950.
Volum 141.
Hefte 3.
s.e16-e16.
DOI: 10.1093/brain/awx378
Erga, Aleksander Hagen; Bjørnestad, Anders; Tysnes, Ole-Bjørn; Alves, Guido; Pedersen, Kenn Freddy
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Is psychosis associated with impulse control disorders in Parkinson's disease?.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 53.
s.110-111.
Gjerde, Kristian Varden; Müller, Bernd; Skeie, Geir Olve; Assmus, Jörg; Alves, Guido Werner; Tysnes, Ole-Bjørn
(2018)
Hyposmia and cognitive decline in early Parkinson's disease.
Olaviken-konferansen;
2018-10-24 - 2018-10-25.
Alves, Guido; Bonanni, Laura
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Neurofilament light: A heavyweight diagnostic biomarker in neurodegenerative parkinsonism?.Neurology.
ISSN 0028-3878.
Volum 88.
Hefte 10.
s.922-923.