Johannes Lange
Adjunct Associate Professor
Contact
Email: johannes.lange@uis.no
Department
Faculty of Science and Technology
Department of Chemistry, Bioscience and Environmental Engineering
Publications
Vitenskapelige publikasjoner
Pedersen, Camilla Christina; Ushakova, Anastasia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Blennow, Kaj; Zetterberg, Henrik; Maple-Grødem, Jodi; Lange, Johannes
(2024)
Serum neurofilament light at diagnosis: a prognostic indicator for accelerated disease progression in Parkinson’s Disease.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 10.
Meng, Jie; Yang, Xiu Mei; Scheer, Oliver; Lange, Johannes; Müller, Heidi; Bürger, Susanne; Rothemund, Sven; Younis, Ruaa; Unterlauft, Jan D.; Eichler, Wolfram
(2024)
Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons.Investigative Ophthalmology and Visual Science.
ISSN 0146-0404.
Volum 65.
Hefte 10.
Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes
(2023)
Seed Amplification Assay as a Diagnostic Tool in Newly-Diagnosed Parkinson's Disease.Journal of Parkinson's Disease.
ISSN 1877-7171.
Volum 13.
Hefte 5.
s.841-844.
DOI: 10.3233/JPD-230065
Maple-Grødem, Jodi; Ushakova, Anastasia; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner; Lange, Johannes
(2023)
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach.Neurobiology of Disease.
ISSN 0969-9961.
Volum 186.
Pedersen, Camilla Christina; Ushakova, Anastasia; Skogseth, Ragnhild Eide; Alves, Guido Werner; Tysnes, Ole-Bjørn; Aarsland, Dag; Lange, Johannes; Maple-Grødem, Jodi
(2023)
Inflammatory biomarkers in newly diagnosed patients with Parkinson’s disease and related neurodegenerative disorders.Neurology: Neuroimmunology and neuroinflammation.
ISSN 2332-7812.
Volum 10.
Hefte 4.
Tufekcioglu, Zeynep; Lange, Johannes; Pedersen, Kenn Freddy; Tysnes, Ole-Bjørn; Alves, Guido Werner; Emre, Murat
(2023)
Cognitive Profile in Parkinson’s Disease Dementia Patients with Low versus Normal Cerebrospinal Fluid Amyloid Beta.Dementia and Geriatric Cognitive Disorders Extra.
ISSN 1664-5464.
Volum 13.
Hefte 1.
s.39-47.
DOI: 10.1159/000534552
Pedersen, Kenn Freddy; Lange, Johannes; Fiske, Eldbjørg
(2023)
Norsk Parkinsonregister og biobank.Norsk Epidemiologi.
ISSN 0803-2491.
Volum 31.
Hefte 1-2.
s.43-47.
Oftedal, Linn Silje Wathne; Maple-Grødem, Jodi; Dalen, Ingvild; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes
(2022)
Association of CSF Glucocerebrosidase Activity with the Risk of Incident Dementia in Patients with Parkinson Disease.Neurology.
ISSN 0028-3878.
Volum 100.
Hefte 4.
s.e388-e395.
Pedersen, Camilla Christina; Lange, Johannes; Førland, Marthe Gurine; Macleod, Angus D.; Alves, Guido Werner; Maple-Grødem, Jodi
(2021)
A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease.NPJ Parkinson's Disease.
ISSN 2373-8057.
Volum 7.
Szwedo, Aleksandra Anna; Pedersen, Camilla Christina; Ushakova, Anastasia; Forsgren, Lars; Tysnes, Ole-Bjørn; Counsell, Carl E.; Alves, Guido Werner; Lange, Johannes; Macleod, Angus D.; Maple-Grødem, Jodi
(2021)
Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients.Frontiers in Neurology.
ISSN 1664-2295.
Volum 11.
s.1-7.
Oftedal, Linn; Maple-Grødem, Jodi; Førland, Marthe Gurine; Alves, Guido Werner; Lange, Johannes
(2020)
Validation and assessment of preanalytical factors of a fluorometric in vitro assay for glucocerebrosidase activity in human cerebrospinal fluid.Scientific Reports.
ISSN 2045-2322.
Volum 10.
s.1-8.
Rajkumar, Anto P.; Hye, Abdul; Lange, Johannes; Manesh, Yazmin Rashid; Ballard, Clive; Fladby, Tormod; Aarsland, Dag
(2020)
Next-generation RNA-sequencing of serum small extracellular vesicles discovers potential diagnostic biomarkers for dementia with Lewy bodies.The American journal of geriatric psychiatry.
ISSN 1064-7481.
s.1-12.
Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir
(2019)
Combinatory microRNA serum signatures as classifiers of Parkinson's disease.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 64.
s.202-210.
Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes
(2019)
The value of cerebrospinal fluid alpha-synuclein and the tau/alpha-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology.European Journal of Neurology.
ISSN 1351-5101.
Volum 27.
Hefte 1.
s.43-50.
DOI: 10.1111/ene.14032
Eichler, Wolfram; Lohrenz, Andrea; Simon, Kay-Uwe; Krohn, Sandra; Lange, Johannes; Bürger, Susanne; Liebscher, Inés
(2019)
The role of ADGRE5/CD97 in human retinal pigment epithelial cell growth and survival.Annals of the New York Academy of Sciences.
ISSN 0077-8923.
DOI: 10.1111/nyas.14210
Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse
(2019)
Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia.International Journal of Tryptophan Research (IJTR).
ISSN 1178-6469.
Volum 12.
s.1-9.
Førland, Marthe Gurine; Öhrfelt, Annika; Dalen, Ingvild; Tysnes, Ole-Bjørn; Blennow, Kaj; Zetterberg, Henrik; Pedersen, Kenn Freddy; Alves, Guido; Lange, Johannes
(2018)
Evolution of cerebrospinal fluid total α-synuclein in Parkinson's disease.Parkinsonism & Related Disorders.
ISSN 1353-8020.
Volum 49.
s.4-8.
Herlofson, Karen; Heijnen, Cobi Johanna; Lange, Johannes; Alves, Guido; Tysnes, Ole-Bjørn; Friedman, Joseph Harold; Fagundes, Christopher P.
(2018)
Inflammation and fatigue in early, untreated Parkinson's Disease.Acta Neurologica Scandinavica.
ISSN 0001-6314.
Volum 138.
Hefte 5.
s.394-399.
DOI: 10.1111/ane.12977
Førland, Marthe Gurine; Öhrfelt, Annika; Oftedal, Linn Silje Wathne; Tysnes, Ole-Bjørn; Larsen, Jan Petter; Blennow, Kaj; Zetterberg, Henrik; Alves, Guido; Lange, Johannes
(2016)
Validation of a new assay for α-synuclein detection in cerebrospinal fluid.Clinical Chemistry and Laboratory Medicine.
ISSN 1434-6621.
Volum 55.
Hefte 2.
s.254-260.
Lange, Johannes; Lunde, Kristin Aaser; Sletten, Camilla Johanne; Møller, Simon Geir; Tysnes, Ole-Bjørn; Alves, Guido; Larsen, Jan Petter; Maple-Grødem, Jodi
(2015)
Association of a BACE1 gene polymorphism with Parkinson's disease in a Norwegian population.Parkinson's Disease.
ISSN 2090-8083.
Volum 2015:973298.
DOI: 10.1155/2015/973298
Alves, Guido; Lange, Johannes; Blennow, Kaj; Zetterberg, Henrik; Andreasson, Ulf; Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Larsen, Jan Petter; Pedersen, Kenn Freddy
(2014)
CSF Aβ42 predicts early-onset dementia in Parkinson disease.Neurology.
ISSN 0028-3878.
Volum 82.
Hefte 20.
s.1784-1790.
Yafai, Yousef; Iandiev, Ianors; Lange, Johannes; Unterlauft, Jan Darius; Wiedemann, Peter; Bringmann, Andreas; Reichenbach, Andreas; Eichler, Wolfram
(2014)
Müller glial cells inhibit proliferation of retinal endothelial cells via TGF-β2 and Smad signaling.Glia.
ISSN 0894-1491.
Volum 62.
Hefte 9.
s.1476-1485.
DOI: 10.1002/glia.22694
Alves, Guido; Pedersen, Kenn Freddy; Bloem, Bastiaan R.; Blennow, Kaj; Zetterberg, Henrik; Borm, George F.; Dalaker, Turi Olene; Beyer, Mona Kristiansen; Aarsland, Dag; Andreasson, Ulf; Lange, Johannes; Tysnes, Ole-Bjørn; Zivadinov, Robert; Larsen, Jan Petter
(2013)
Cerebrospinal fluid amyloid-beta and phenotypic heterogeneity in de novo Parkinson's disease.Journal of Neurology, Neurosurgery and Psychiatry.
ISSN 0022-3050.
Volum 84.
Hefte 5.
s.537-543.
Yafai, Yousef; Iandiev, Ianors; Lange, Johannes; Yang, Xiu Mei; Wiedemann, Peter; Bringmann, Andreas; Eichler, Wolfram
(2013)
Basic Fibroblast Growth Factor Contributes to a Shift in the Angioregulatory Activity of Retinal Glial (Muller) Cells.PLOS ONE.
ISSN 1932-6203.
Volum 8.
Hefte 7.
Lange, Johannes; Yafai, Yousef; Noack, André; Yang, Xiu Mei; Munk, Anne-Britta; Krohn, Sandra; Iandiev, Ianors; Wiedemann, Peter; Reichenbach, Andreas; Eichler, Wolfram
(2012)
The axon guidance molecule Netrin-4 is expressed by Muller cells and contributes to angiogenesis in the retina.Glia.
ISSN 0894-1491.
Volum 60.
Hefte 10.
s.1567-1578.
DOI: 10.1002/glia.22376
Formidling
Eidem, Live Egeland; Birkeland, Even; Austdal, Marie; Bårdsen, Kjetil; Lange, Johannes; Alves, Guido Werner; Berven, Frode Steingrimsen; Nilsen, Mari Mæland; Herlofson, Karen; Tysnes, Ole-Bjørn; Omdal, Roald
(2024)
Fatigue in Parkinson's Disease: A Proteomic Study of Cerebrospinal Fluid.Movement Disorders.
ISSN 0885-3185.
Volum 39.
Hefte 4.
DOI: 10.1002/mds.29715
Oftedal, Linn Silje Wathne; Lange, Johannes; Pedersen, Kenn Freddy; Erga, Aleksander Hagen; Dalen, Ingvild; Tysnes, Ole-Bjørn; Alves, Guido Werner; Maple-Grødem, Jodi
(2023)
Early GCase activity is a predictor of long-term cognitive decline in Parkinson’s disease.Translational Neurodegeneration.
ISSN 2096-6466.
Volum 12.
Hefte 1.